To me, logic says you should call the airline and see specifically how they're rerouting the flight to avoid this kind of danger. If you can't get an answer, don't get a satisfactory answer, or don't know how to tell what answer would satisfy you, book another flight.

In general, flying is safer than either driving or walking in urban areas. But most flights don't happen over not-technically-but-actually-definitely war zones. So ... make sure whatever flight you're on avoids the area entirely.