I agree this is the right question, but for the opposite argument. False positives in early stage ventures, in my experience, can be quickly and actively remedied. I've seen people fired less than two weeks after being hired without a substantial impact on the rest of the team or the product. If you can do this, you have a lot more freedom to take risks with new hires.

In a larger organization, if you hire someone, you're stuck with them in almost all cases. So be picky.