You can see pixels up close on a 1080p screen if you have good eyesight, but that's not the way you're supposed to work with a screen as a matter of ergonomics. Even on a laptop, you're always looking at the screen as a whole, not just seeing a tiny portion of it in your field of view.
That's exactly what I meant by "up close". A 27'' monitor should be 3 or 4 ft. away in order to comfortably look at the whole screen. Any other choice is terrible ergonomics.
Glad you know how my eyes work. You probably will say next that I can’t see the refresh.