I have read that southern Europeans often have a much harsher response to illness (higher fever / skin going bright red / that kind of thing), and that this is speculated to be a leftover from the Black Plague.

I can't find a reference to it now, though, and if there was a term for the exaggerated response I don't remember it.

It's possible that my memory confused a harsher fever response to normal illnesses with familial mediterranean fever:

https://www.genome.gov/news/news-release/genomic-variation-c...

https://www.nih.gov/news-events/nih-research-matters/how-bla...