What would it take to create the “mRNA moment” for antifungal drugs—something that accelerates both funding and discovery at scale? Are there promising platforms (e.g. AI drug discovery, CRISPR screening, biofoundries) that could shift the economics of developing treatments for rare but rising fungal threats?
I’m an outsider to that field, but I don’t see a reason why mRNA can’t be the “mRNA moment” - fungal vaccines are possible, and if you can find the right target protein you can make an mRNA vaccine against a particular infection.
I think it’s just a matter of priorities and funding, which fungal infections as a whole don’t get enough of in general.
