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There is no claim that each drug costs 1$ billion. If you stop after 1-2 years of development you might have wasted some millions, if you stop after 3-4 years you wasted tens of millions and so on. The 10% success is still very low, because you can still fail after 10 years (potentially investing a lot)

If you are interested in the topic, for example for oncology: https://jamanetwork.com/journals/jamanetworkopen/fullarticle... , to quote "Failed drug development in oncology incurs substantial expense. At an industry level, an estimated $50 billion to $60 billion is spent annually on failed oncology trials."

There is no "oracle" that says invest 50 million (or 100 million or 1 billion) in X or Y and it will succeed (in pharma or other domains). And this is not exclusively because of capitalism, it is because doing some things is hard.



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