I would think the US, due to its size and resources, should be able to produce most things. At least something like cars, which doesn’t depend on weather or other rare qualities, but rather just an educated and sufficient workforce.
Few nations in the world get to have that kind of luxury.
I'm no car manufacturer, nor do I work in the industry, but seems to me quite a bit of national resources are missing if the US wanted to be completely independent when making cars, resources like lithium, cobalt, natural rubber and even rare earth elements. Probably more I'm missing.