Most real-life applications of discoveries that advanced humanity have been done by for-profit organizations. Applied science.
Most advances in human history have been done by individuals who were simply passionate about a topic, and they did not do it for money. Theoretical science.
Although honestly, I think we shouldn't talk about "most" throughout history, because democracy/free trade/capitalism is pretty new, so we need to normalize for that.
Google: 2 guys doing a PHD, work on their thesis, not for money (Theory). They later realize they could turn this into a business (Application).
Programming language, OSS, and platforms: A few friends or a lone guy/gal know they can do something way better or create a programming language or a database system more powerful than what is out there (Theory). Millions of other programmers use the language, tools and build powerful businesses such as Facebook and Twitter around it(Application). This is probably why you can do a startup today for $0 upfront cost.
I doubt Einstein spent countless hours working his brains off for money, Darwin did not go across continents to study the origin of species for money, Bethoveen did not write symphonies solely for money. Yet many other talented individuals have used their findings and made loads of money along the way.
Considering Googler guys never even published their thesis... they went commercial pretty quick after hitting their idea, and dedicated the largest portion of their lives to the business end.
Bell Lab's had the most Nobel prizes of any for profit institution at 7. There's 13 non-for profit organization that have eight or more. Even if you drop out the political Nobels (Peace and Economics), there's still 11 entities out there besting the best that for-profit institutions have to offer. Also, most of these Nobels have been in the past hundred years, so no need to normalize out the advent of democracy.
It's true that for profit enterprises take these discoveries (e.g. Giant Magnetoresistence, MRI, Fiber Optics, CCDs) and ramp them up for mass production. However, they're still tweaking the major break-through made by people focused on things besides the personal accumulation of wealth.
Though not necessarily their goal, a side of this story you don't mention is income via royalties. I have worked with multiple Bell labs alumnus who are financially very secure in part because of their work there.
As much as software patents irk common sense, the notion of IP protection really does seem reasonable here. There are people who do research for reasons beyond personal profit. They actually do deserve licensing fees.
Most advances in human history have been done by individuals who were simply passionate about a topic, and they did not do it for money. Theoretical science.