Yeah, I would imagine they would do the minimally invasive surgey to remove as much tumor as possible and then do the immune treatment after. Maybe it would make sense to a biopsy and just the immune treatment, but my guess is it would be mkre effective the first way. At least in my personal experience with this kind of thing I would think this could improve survival rates and reduce disabilities caused or worsened by surgery by not having to achive clean margin removal of the tumor. But who knows. Maybe in the future they can extract enough tumor DNA from blood draws to create the target.