I don't think what you're talking about is aliasing: it's more to do with the statistics of sampling. Though even then I still don't quite get what you mean: if a bounds check is 20% of your runtime then you're going to see it in your samples pretty quickly. If it's a small enough fraction of your runtime that you don't expect to see it in millions of samples, then why is it relevant to your performance? Now, if you're worried about latency outliers, I can see why sampling may not be a useful tool, but again I don't think the reason for that is really aliasing.