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> single-dose trial of standard adult doses of the three drugs (30 mg of MPH, 15 mg of DEX, and 200 mg of MOD) and PLC, administered before being asked to solve eight instances of the knapsack task. Doses are at the high end of those administered in clinical practice, reflecting typical doses in nonmedical settings, where use tends to be occasional rather than chronic.

I’ve taken methylphenidate aka Ritalin (MPH) and dexteroampheramine aka Adderall (DEX) and my largest prescription was less than half of these doses.

If I take a dose of 15mg of MPH after a break of 10 days, I’ll be jittery, irritable, and a bit over-active. I imagine taking 30mg for someone neurotypical who’s never taken it before would be closer to a subdued but sustained hit of cocaine. I wouldn’t imagine anyone performing well in this trial, I probably wouldn’t either with a 30-day break beforehand. I don’t know where they’re getting this “typical adult dose for non-prescription use”… I have a neurotypical friend who takes 10mg of adderall as a party drug at raves.



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