As far as i understand, psylocin and LSD have never been shown to be dangerous, in combination with any drug with possible exception to MAOI _maybe_. There are interactions that make it less intense and interactions that make it more intense. The only real danger is that you'll do something bad while in the state, not that the state will actually harm you.
So it's perfectly reasonable for someone to take a low dose of LSD while on antidepressants. The worst I've ever heard of occurring is that you just won't feel it at all. It's a targeted agonist of multiple serotonin receptors, i don't believe it actually releases any large flood of serotonin. Something like MDMA though _is_ very dangerous to take with SSRIs due to serotonin syndrome.
I've known many people to do psychedelics while on antidepressants and non of them have ever approached the levels of danger or concern that I've seen for people doing MDMA while not on anything else. The traditional psychedelics (LSD, shrooms) are remarkably safe and there's no reason to act like this person is being dumb or disingenuous for doing them in their circumstance. If you have research to the contrary I'd certainly welcome the opportunity to learn
But I have (likely) permanent HPPD - particularly when I take my adhd meds I can get some motion inpainting, geometry visuals, and turning off the lights at night looks like a "shower of colors", and also white looks simultaneously red/blue/green/purple (the color you see after looking at a really bright light and looking away).
It's not currently causing issues for me but it is a real thing. MRI shows no abnormalities, eye exam also shows nothing odd. The visuals are almost identical to light lsd visuals. I'm 100% aware they aren't "real", none of my doctor's believe it's psychosis.
I'm also 100% convinced that chronic psychedelic and possibly chronic marijuana usage contributes to schizophrenia.
And I'm certain you can get real PTSD from a bad trip.
I have no idea what extent the medication combo did, but with or without antidepressents, I don't want to say it's "safe". I'm not saying it's dangerous, but I don't think it's harmless.
Also smoking marijuana with lsd makes it like 10x more intense, and I have a feeling that also has a chance at shifting the harm potential.
So it's perfectly reasonable for someone to take a low dose of LSD while on antidepressants. The worst I've ever heard of occurring is that you just won't feel it at all. It's a targeted agonist of multiple serotonin receptors, i don't believe it actually releases any large flood of serotonin. Something like MDMA though _is_ very dangerous to take with SSRIs due to serotonin syndrome.
I've known many people to do psychedelics while on antidepressants and non of them have ever approached the levels of danger or concern that I've seen for people doing MDMA while not on anything else. The traditional psychedelics (LSD, shrooms) are remarkably safe and there's no reason to act like this person is being dumb or disingenuous for doing them in their circumstance. If you have research to the contrary I'd certainly welcome the opportunity to learn