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The idea that you could just take a pill one time and be "protected from aging" or something sounds ludicrous. Would be interested to see people reproduce these results and have them supposedly transfer over to humans. Humans are a much longer time scale.

I always go back to the SENS concept of having several different problems to solve related to built up damage, cells that won't die, etc.



It's definitely not a one-time thing... There's a fascinating Radiolab episode on the the history of Rapomycin, including discussions of the mechanism of action: https://radiolab.org/episodes/dirty-drug-and-ice-cream-tub

The basic hypothesis is that cells operate in two modes, one storing up stuff in times of plenty, and a second mode which uses up the stores and cleans up, active during lean times. mTor is supposed to be the chemical signal which indicates which mode to act in; it's inhibited by both fasting and rapomycin.


People used to feel the same way about vaccines.

Now we have vaccines that eliminate a specific form of cancer.

Perhaps we will find a way to pack all the different treatments for the various SENS forms of aging into a single one-time pill.

Maybe it will just be self-replicating nanobots.

What a fascinating time we live in where we can actually start to make educated guesses about the viability and timeframe for these kinds of things.




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