There have been many attempts to find the right phone interface for eink displays. So far, I like the Light Phone 2 the best; it runs a version of Android that's totally stripped down to have a streamlined set of features that work well on eink.
To me the main benefit of an e-Ink display is the ability to read it for hours without eye strain. Judging by the size of the Light Phone's screen, it seems that the only benefit there is battery life.
https://www.thelightphone.com/