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Wonder what impact that could eventually have on people with Sickle Cell or Beta thalassemia (or the rare case that hits the genetic jackpot and has both).


My bet is before this particular branch of technology reaches maturity, the CRISPR tech tree will have solved that particular problem


I don't follow medical tech religiously but read the original article and thought it relevant (I have a friend that actually has both conditions and the treatment for it is brutal).

Looks like I have more to read up on, thanks!


I think gene therapy is going to solve that well before an approach like this. Those two are some of the lower hanging fruit to go after (well defined, clear mutation in a single gene, etc) and theres a bunch of therapies already in the pipeline to cure them.


It's really not. There were people long retired before I hit the workplace and I'm fast approaching 50.

There is a combination of seemingly relentless growth in demand and people deciding they've had enough and hitting the management track however. At least in London/finance. The number of people I started with that are still coding on a daily basis is very small.


http://www.dirtydicks.co.uk/

Bishopsgate, nearest tube is Liverpool Street. Mind your head there are some low beams in there.


I think you misunderstood what I meant, I couldn't find Dirty Dicks in the article... :)


Did you expect her to visit absolutely everything in London in a couple of days of visit? That's not going to be possible, is it?


Liverpool Station is really not that offbeat.


* Liverpool Street station.

Heading to Liverpool station would be an expensive and time-consuming mistake if you were aiming for Bishopsgate.


There are hundreds and hundreds of 'not offbeat' places to visit in London. You're not going to include them all in a travelog of a few days are you? It's not realistic to demand to know why someone hasn't included whatever your favourite place is.


Okay, dad.


I lived in London most of my life, I've never been to this place.

Why is it important to visit this pub?



Adding bad ideas together ironically can create good concepts. Realistic bueracracy story centered on a bueracrat and say story set in heaven both would be boring separately. A harried angelic bueracrat trying to keep up with an endless stream of weird requests from "good people" throughout history, deal with people wanting to meet their ancestors, descendants, and famed figures and keeping them happy when they would get along terribly from differing values or finding out they were condemned to hell? Already a comedy with surprising depth in an elevator pitch.


I was working at a university in the UK and got to see Mosaic in 93(I think, it was a very early beta). I said to the main sysadmin "It's very pretty, but it will never replace gopher". He still reminds me of that fact occasionally. Even then it wasn't as fast or efficient to get data/documents out of and I stand by that judgement.



I think the NSA would know if that was the case and be able to pass that information along.


Very likely, although they probably wouldn't pass this on the public.


>As an aside: don't forget the largest major anti-condom propagandists is not African at all (ie, the Catholic church).

That would be the curch that also goes on about abstinence before marriage and monogamy afterwards? Never understood why the church gets beaten up for that (not a fan of the stance on condom use but this implies people "religously" follow one of their rules while blatantly ignoring others).


The difference is that you can't really convince people to practice abstinence and monogamy. You can quite easily convince people to not use condoms. Failing to take this into account when you are in a position of authority is unethical at best. Spreading misinformation such as HIV being able to get through condoms is plain old evil.


If you abstain you have no chance of getting pregnant. It depends: http://skeptics.stackexchange.com/questions/3167/do-condoms-... .


Sex is part of human nature. It used to happen before Humans invented the notion of marriage. The church is trying to stop something that is intrinsically a part of us, that is a bad strategy and is actively making the world a WORSE place.

A better idea would be to encourage people to use condoms. This does not circumvent human nature and has a much better chance of working.

Don't defend ill thought out policy with bad logic.


Violence and war are also parts of human nature, that doesn't mean religions should give up preaching peace and forgiveness.


Most people don't wake up in the morning with the urge to fight someone, a lot of people do wake up with the urge to have sex. Sex, like voilence, will always happen. We need to find a way to work with what we've got rather than trying to suppress are human needs.


> people "religously" follow one of their rules while blatantly ignoring others

That's mostly how it works. People follow the rules they like and ignore the ones they don't.


It's not just about (not) following rules. When you have no access to condoms because of the church, it doesn't matter what you think and follow.


> this implies people "religously" follow one of their rules while blatantly ignoring others

Is that so implausible?


Ballmer a visionary founder? That's wrong on at least two counts out of a possible three.


Do you remember that "developers developers developers .." bit. Can you recall any other executive of a multi-billion corp who was that passionate about developers? I appreciated a executive who was that passionate about third party developers. Also, he was part of a founding team that built a software giant ! I am a *NIX/Java guy but I appreciate Microsoft SDKs and Tool sets. Ballmer has not been as successful as hoped , but he is ok in my book.


Yep. It's pretty clear that of the big houses out there, only Microsoft really gives two shits about every developer, ninja rockstar or punchclock.


Ballmer was at Microsoft when they were sub 50 people. Maybe he's not a visionary founder but potentially a visionary foundational employee? Considering how long he's been at the company, I'm not sure how one separates Microsoft's high in the 90s from Ballmer.


A machine with an NVidia Titan card is top end? I'd have said overkill. I'm not sure why you'd want that for a gaming rig over a GTX780.


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