I'm surprised how low suicide rates are at 2%. If I were an old sick person and steadily becoming more of a burden, there's no way in hell I would just leave it to nature to decide when I die, or let the profit-maximizing hospital bureaucracy make that call for me. I'm sure some old folk are afraid that suicide will send them to hell, as if God wouldn't understand.
Its more like AI has made content from accounts created after 2022-2023 difficult to trust even more than the previous error of bots. Its like how nuclear tests made all steel not sourced from shipwrecks have too high of radiation to be used for high sensitivity radiation detectors
my comment expressed neither belief nor hope that God was real, just that you were arrogant to deny God's existence but still claim to know what He is thinking.
It's a Tesla fanboy/investor website. They used to have the $TSLA stock ticker right on the front page. Commentor opinions on any other car company are even more useless than the average internet opinion.
Transplanted kidneys get rejected by the recipient's immune system eventually, you'd really need to clone the kidney from the individual's DNA to solve the rejection problem. There's also been some success with integrating the DNA from the kidney donor (a human) into the recipient's bone marrow to stop the rejection process, but I hear it can be a brutal procedure in which the original bone marrow must be destroyed using chemotherapy or radiation.
> and really hope it lasts until something like kidney cloning is a thing.
There was another technology under development, colloquially called the 'ghost heart' [1]. It uses a dead heart that's similar to a human's, most likely a pig's heart (I speculate that an unused human heart can also be used). They remove all the cells from the heart using a soap-like substance to obtain a ghostly white colored scaffolding of a heart (probably made of collagen). Then they use the recipient's own stem cells to grow heart muscles, blood vessels, etc on the scaffold. The process to get it to work like a human heart seems complicated, but doable. As you can guess, this heart is fully immunocompatible with the patient and doesn't require immunosuppressants like after a regular transplant. I imagine that this can eventually be replicated for any organ and that the improvement in the patient's quality of life it will bring is unthinkable in the current state of affairs. I'm not sure about the progress and current state of this technology, but several articles do turn up on searching.
Any time I haven’t heard about a tech for ten years I assume it didn’t work. I think I first heard of this stuff around ten years ago. At the time I think they were focused on kidneys. But those have a lot of complex plumbing.
As an outsider, who is either missing a mountain of context, or not so close to the problem they can’t see it, I would assume a better tack would be growing ghost arteries for bypasses and aneurism repair operations. Ghost intestines for reconstruction surgery for people with cancer or massive internal trauma. You’d have a simpler organ to reproduce, but in the artery case you’d likely have to also work turnaround time. Heart failure can be slow, but bypass surgery is often scheduled as either urgent or emergency (I just had a convo with a man who wasn’t allowed to leave the hospital after an angiogram showed he was one stairwell away from a fatal heart attack). But not having to harvest material from the thigh before surgery begins should shorten the surgery and reduce complications. You can have as much artery as you want for the surgery. You could have spares.
The article I cited is from 2022. At that time, the principal scientist had left the academia and was working to commercialize it. So I'm guessing it's still within your decade threshold? Besides, perhaps that threshold should be longer under the current circumstances. One of the greatest medical advancement of the recent times is the mRNA vaccine technology. But it's true origin is in the 1970s. They were solving numerous related problems in the meantime, though it could have been finished sooner had someone invested in it as intensely as they did during the pandemic.
Looking at bibliographies, it seems like a lot of the research for decellularization was 2011, 2013, and a handful after. So they were still working on getting a clean substrate while working on how to fill it back in.
It’s a big problem, but still seems like they’re swinging for the fences when they could save people in the short term while working on organs.
Interesting! I just remembered that there is another team that's working on plant based scaffolds (cellulose scaffolds from leaves like spinach) [1]. This one is from 2017. So I'm guessing that the interest in the technology hasn't waned yet. I also wonder if any biocompatible scaffolds can be 3D printed, rather than having to decellularize the available ones.
It's not entirely impossible that a broadly compatible tissue could be engineered - in a more through version of the same process that yielded those "somewhat human-compatible" pig organs.
That's a part of the reason why this tech is so promising. If we can already target immune incompatibilities to make "elongated pigs" with organs that fit human bodies somewhat, then what are the limits?
It's not worth anyone's time to meticulously fact check known (and I'm being kind here) 'exaggerator' Sam Altman, because by the time you're done, he's already spread 10 more 'exaggerations'.
They took 1 step at a time instead of trying to take multiple steps at a time, how is that a bad thing. They're obviously getting things prep'd for Chrome agents and Gemini 3.
I think if Google trained current models on private data, confidential info would leak constantly, it would be an absolute trainwreck. If Gemini leaked your Gmail and Chrome activity, Google would get sued and regulated into oblivion.
But Google needs to leave this option open in the future, in case they have to go all-in on an arms-race against China, if Chinese AI starts becoming an actual threat somehow. And it's easy to predict the USA gov would prioritize that race over privacy concerns.
This response is good but the more general problem is that people are in "It doesn't look like anything to me" mode like Westworld robots seeing advanced technology. If there's a way to snap people out of that, I've never seen it.
I think it's just a simple case of "when times are good, people cooperate, when times are bad, they turn on each other."
And right now, we're somewhere in-between, where things have stagnated but nothing's catastrophic yet. People turn on each other over tiny symbols, but very few people are actually choosing violence over words.
The problem is that the default trajectory is currently downward. Stocks grow at 6% while wages lose ground to inflation, and no one is doing anything to stop this (most of them don't even seem to realize this, they just have some intuition that the economy is being not-nice), so things are probably going to get worse until some Next-Big-Thing finally shakes things up.
Right now it's the at-risk people, who maybe were going to fall into some rabbit-hole anyway.
When it's the typical/average people that start getting hooked like this, that's going to be a whole new headache. Really hoping things don't play out like that...
